Dosage ; Hypertension, initially 25mg twice daily, increased by 25-50mg daily at intervals of 2 weeks;
max. daily dose 200 mg in 2-3 divided doses.
Combinations ; - see below
| Indoramin More info | |
|---|---|
| Drug Indication | Hypertension; benign prostatic hyperplasia. |
| Precautions | Avoid alcohol (enhances rate and extent of absorption); control incipient heart failure before initiating indoramin; elderly; Parkinsons disease (extrapyramidal disorders reported); epilepsy (convulsions in animal studies); history of depression; cataract surgery (risk of intra-operative floppy iris syndrome); drowsiness may affect performance of skilled tasks (e.g. driving);effects of alcohol may be enhanced. |
| Contra-Indications | Established heart failure; hepatic impairment; renal impairment; pregnancy: no evidence of teratogenicity; manufacturers advise use only when potential benefit outweighs risk; breast-feeding. |
| Side Effects | sedation; less commonly fatigue, weight gain, failure of ejaculation; extrapyramidal disorders, urinary frequency, and incontinence. |
| Dosage | Hypertension, initially 25mg twice daily, increased by 25-50mg daily at intervals of 2 weeks; max. daily dose 200 mg in 2-3 divided doses. |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Alpha-adrenoceptor blocking agents |